Drug Information

Drug General Information
Drug ID
D0E2FZ
Former ID
DIB005599
Drug Name
ICA-69673
Synonyms
ICA-069673; Ion channel modulators (epilepsy), ICAgen; Ion channel modulators, ICAgen/ArQule
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Preclinical [546904]
Company
Icagen Inc
Canonical SMILES
c1(ncc(cn1)NC(=O)c1ccc(c(c1)F)F)Cl
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily KQT member 3 Target Info Modulator
Potassium voltage-gated channel subfamily KQT member 2 Target Info Modulator
KEGG Pathway Cholinergic synapsehsa04725:Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Reactome Voltage gated Potassium channels
Interaction between L1 and AnkyrinsR-HSA-1296072:Voltage gated Potassium channels
Interaction between L1 and Ankyrins
WikiPathways Potassium Channels
L1CAM interactionsWP2669:Potassium Channels
L1CAM interactions
References
Ref 546904Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011004)

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