Drug Information

Drug General Information
Drug ID
D0D9OC
Former ID
DNC007394
Drug Name
2-chloro-6(methylamino)purine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528751]
Formula
C6H6ClN5
Canonical SMILES
CNC1=NC(=NC2=C1NC=N2)Cl
InChI
1S/C6H6ClN5/c1-8-4-3-5(10-2-9-3)12-6(7)11-4/h2H,1H3,(H2,8,9,10,11,12)
InChIKey
RIAVUEFUPHOGJY-UHFFFAOYSA-N
PubChem Compound ID
4584789
Target and Pathway
Target(s) Xanthine dehydrogenase/oxidase Target Info Inhibitor [528751]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Guanosine nucleotides degradation
Adenosine nucleotides degradation
Retinoate biosynthesis II
KEGG Pathway Purine metabolism
Caffeine metabolism
Drug metabolism - other enzymes
Metabolic pathways
Peroxisome
PANTHER Pathway Adenine and hypoxanthine salvage pathway
Purine metabolism
PathWhiz Pathway Caffeine Metabolism
Purine Metabolism
Reactome Purine catabolism
WikiPathways Oxidative Stress
Effects of Nitric Oxide
Metabolism of nucleotides
Selenium Micronutrient Network
References
Ref 528751Bioorg Med Chem. 2007 May 15;15(10):3450-6. Epub 2007 Mar 12.The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
Ref 528751Bioorg Med Chem. 2007 May 15;15(10):3450-6. Epub 2007 Mar 12.The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.