Drug Information

Drug General Information
Drug ID
D0D7KE
Former ID
DNC014332
Drug Name
4'-(4-Fluorobenzensulfonamide)-4-hydroxychalcone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530713]
Formula
C21H16FNO4S
Canonical SMILES
C1=CC(=CC=C1C=CC(=O)C2=CC=C(C=C2)NS(=O)(=O)C3=CC=C(C=C3<br />)F)O
InChI
1S/C21H16FNO4S/c22-17-6-12-20(13-7-17)28(26,27)23-18-8-4-16(5-9-18)21(25)14-3-15-1-10-19(24)11-2-15/h1-14,23-24H/b14-3+
InChIKey
SRDYAWAEKAHCHN-LZWSPWQCSA-N
PubChem Compound ID
24757297
Target and Pathway
Target(s) Tyrosine oxidase Target Info Inhibitor [530713]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 530713Eur J Med Chem. 2010 May;45(5):2010-7. Epub 2010 Jan 28.Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone.
Ref 530713Eur J Med Chem. 2010 May;45(5):2010-7. Epub 2010 Jan 28.Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone.

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