Drug Information

Drug General Information
Drug ID
D0CY6E
Former ID
DNC006785
Drug Name
2-(4-(benzenesulfonyl)phenyl)-1-aminoethane
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528373]
Formula
C14H15NO2S
Canonical SMILES
C1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)CCN
InChI
1S/C14H15NO2S/c15-11-10-12-6-8-14(9-7-12)18(16,17)13-4-2-1-3-5-13/h1-9H,10-11,15H2
InChIKey
YNFGKNGJUDQMQL-UHFFFAOYSA-N
PubChem Compound ID
44414681
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [528373]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 528373J Med Chem. 2006 Aug 24;49(17):5217-25.Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.
Ref 528373J Med Chem. 2006 Aug 24;49(17):5217-25.Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.

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