Drug Information

Drug General Information
Drug ID
D0C7GB
Former ID
DNC013011
Drug Name
1-(piperidin-3-ylmethyl)pyridin-2(1H)-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528157]
Formula
C11H16N2O
Canonical SMILES
C1CC(CNC1)CN2C=CC=CC2=O
InChI
1S/C11H16N2O/c14-11-5-1-2-7-13(11)9-10-4-3-6-12-8-10/h1-2,5,7,10,12H,3-4,6,8-9H2
InChIKey
CRXGPVZZFUWGAF-UHFFFAOYSA-N
PubChem Compound ID
44410533
Target and Pathway
Target(s) Neuronal acetylcholinereceptor subunit alpha-2 Target Info Inhibitor [528157]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Nicotinic acetylcholine receptor signaling pathway
Reactome Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 528157J Med Chem. 2006 May 4;49(9):2673-6.Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.
Ref 528157J Med Chem. 2006 May 4;49(9):2673-6.Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.

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