Drug Information

Drug General Information
Drug ID
D0C3TI
Former ID
DIB014522
Drug Name
Resimmune
Synonyms
A-dmDT390-bisFv immunotoxin
Indication Melanoma [ICD9: 172; ICD10:C43] Phase 1/2 [549482]
Company
Angimmune
Target and Pathway
Target(s) T-cell surface glycoprotein CD3 epsilon chain Target Info Modulator
KEGG Pathway Hematopoietic cell lineage
T cell receptor signaling pathway
Chagas disease (American trypanosomiasis)
Measles
HTLV-I infection
Primary immunodeficiency
NetPath Pathway TCR Signaling Pathway
Leptin Signaling Pathway
PANTHER Pathway T cell activation
Pathway Interaction Database TCR signaling in na&#xef
IL12-mediated signaling events
TCR signaling in na&#xef
CXCR4-mediated signaling events
IL23-mediated signaling events
Downstream signaling in na&#xef
IL12 signaling mediated by STAT4
Reactome Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Phosphorylation of CD3 and TCR zeta chains
Translocation of ZAP-70 to Immunological synapse
Generation of second messenger molecules
PD-1 signaling
WikiPathways TCR Signaling Pathway
TCR signaling
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Costimulation by the CD28 family
References
Ref 549482Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800038158)

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