Drug Information

Drug General Information
Drug ID
D0C1NP
Former ID
DIB019520
Drug Name
compound 4g
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531910]
Formula
C13H13NO5
InChI
InChI=1S/C13H13NO5/c1-13(2)11(16)14(12(17)19-13)10(15)8-4-6-9(18-3)7-5-8/h4-7H,1-3H3
InChIKey
ZYRNCIWULACSEK-UHFFFAOYSA-N
PubChem Compound ID
66561876
PubChem Substance ID
152192579, 160673055, 160863194, 252166826
Target and Pathway
Target(s) Leukocyte proteinase-3 Target Info Inhibitor [531910]
Cathepsin G Target Info Inhibitor [531910]
Leukocyte elastase Target Info Inhibitor [531910]
KEGG Pathway Neuroactive ligand-receptor interaction
Lysosome
Renin-angiotensin system
Amoebiasis
Systemic lupus erythematosushsa05202:Transcriptional misregulation in cancer
Systemic lupus erythematosus
Pathway Interaction Database C-MYB transcription factor networkupa_upar_pathway:Urokinase-type plasminogen activator (uPA) and uPAR-mediated signalingupa_upar_pathway:Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
C-MYB transcription factor network
Reactome Common Pathway of Fibrin Clot FormationR-HSA-1474228:Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)R-HSA-1442490:Collagen degradation
Degradation of the extracellular matrix
WikiPathways ACE Inhibitor Pathway
Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)WP2840:Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Human Complement System
Degradation of collagen
References
Ref 531910N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3993-7.
Ref 531910N-Acyl and N-sulfonyloxazolidine-2,4-diones are pseudo-irreversible inhibitors of serine proteases. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3993-7.

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