Drug Information

Drug General Information
Drug ID
D0BN7W
Former ID
DIB002031
Drug Name
Roclatan
Synonyms
PG324
Indication Glaucoma [ICD9: 365; ICD10:H40-H42] Phase 3 [525325]
Company
Aerie pharmaceuticals
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Modulator [1572591]
Rho associated protein kinase Target Info Modulator [1572591]
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 525325ClinicalTrials.gov (NCT02558400) Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension.
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.