Drug Information

Drug General Information
Drug ID
D0B8SS
Former ID
DIB018515
Drug Name
1-stearoyl-lysophosphatidylcholine
Synonyms
LPC 18:0; lysophosphatidylcholine (18:0); stearoyl alpha-lysolecithin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540997]
Formula
C26H54NO7P
InChI
InChI=1S/C26H54NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h25,28H,5-24H2,1-4H3/t25-/m1/s1
InChIKey
IHNKQIMGVNPMTC-RUZDIDTESA-N
PubChem Compound ID
497299
PubChem Substance ID
793528, 7983922, 10314966, 38684807, 57393203, 57405797, 77719472, 109769421, 126529344, 164174515, 164793462, 178102279, 179660965, 194179885, 250133173
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [527346]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 540997(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5651).
Ref 527346Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor. Biochem Biophys Res Commun. 2005 Jan 28;326(4):744-51.

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