Drug Information

Drug General Information
Drug ID
D0B7HX
Former ID
DIB011539
Drug Name
Levosemotiadil
Synonyms
DS-4824; SA-3212; SD-3212
Drug Type
Small molecular drug
Indication Cardiac arrhythmias [ICD9: 427; ICD10:I47-I49] Discontinued in Phase 2 [545959]
Company
Santen Pharmaceutical Co Ltd
Formula
C29H32N2O6S
Canonical SMILES
C1(=O)[C@@H](Sc2c(N1C)cccc2)c1c(ccc(c1)OC)OCCCN(CCOc1cc<br />2c(OCO2)cc1)C.C(=O)(/C=C/C(=O)O)O
PubChem Compound ID
9852564
Target and Pathway
Target(s) Sodium channel Target Info Modulator [525617]
Calcium channel Target Info Modulator [525617]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 545959Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005516)
Ref 525617Binding study of semotiadil and levosemotiadil with alpha(1)-acid glycoprotein using high-performance frontal analysis. Anal Biochem. 1999 Oct 1;274(1):27-33.

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