Drug Information

Drug General Information
Drug ID
D0B4ZT
Former ID
DIB021221
Drug Name
WS-23
Synonyms
WS 23
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539601]
Formula
C10H21NO
InChI
InChI=1S/C10H21NO/c1-7(2)10(5,8(3)4)9(12)11-6/h7-8H,1-6H3,(H,11,12)
InChIKey
RWAXQWRDVUOOGG-UHFFFAOYSA-N
PubChem Compound ID
65300
PubChem Substance ID
3157385, 8189616, 12086170, 15120459, 43122119, 53800994, 75004615, 87560783, 92252351, 104333412, 118845175, 121279124, 125351794, 126687070, 129189982, 135021822, 137021410, 142012453, 152040758, 160798693, 162293286, 162765045, 163403268, 163811853, 163884259, 164832903, 172914230, 175267036, 184585217, 204408658, 223492778, 223516851, 223541918, 223671911, 226420001, 241090401, 252499712
Target and Pathway
Target(s) TRPM8 protein Target Info Activator [526953]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 539601(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2474).
Ref 526953Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45. Epub 2004Feb 2.

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