Drug Information

Drug General Information
Drug ID
D0B1VQ
Former ID
DIB008785
Drug Name
GR-133347
Synonyms
AH-023
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Terminated [545477]
Company
Glaxo Group Research Ltd
Canonical SMILES
C1(c2c(CC(NC(=O)C)C1)cccc2)c1ccccc1
CAS Number
CAS 134865-73-9
Target and Pathway
Target(s) Melatonin receptor Target Info Modulator [550913]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 545477Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003420)
Ref 550913US patent application no. 5,151,446, Substituted 2-amidotetralins as melatonin agonists and antagonists.

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