Drug Information

Drug General Information
Drug ID
D0AT3U
Former ID
DNC006955
Drug Name
N-(4-amino-2-propylquinolin-6-yl)cinnamamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528381]
Formula
C21H21N3O
Canonical SMILES
CCCC1=NC2=C(C=C(C=C2)NC(=O)C=CC3=CC=CC=C3)C(=C1)N
InChI
1S/C21H21N3O/c1-2-6-16-14-19(22)18-13-17(10-11-20(18)23-16)24-21(25)12-9-15-7-4-3-5-8-15/h3-5,7-14H,2,6H2,1H3,(H2,22,23)(H,24,25)/b12-9+
InChIKey
PWQSXBRFDPQGOC-FMIVXFBMSA-N
PubChem Compound ID
44418001
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [528381]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 528381Bioorg Med Chem Lett. 2006 Oct 15;16(20):5275-9. Epub 2006 Aug 17.4-Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1R) antagonists.
Ref 528381Bioorg Med Chem Lett. 2006 Oct 15;16(20):5275-9. Epub 2006 Aug 17.4-Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1R) antagonists.

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