Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0A2NK
|
||||
| Former ID |
DNC004870
|
||||
| Drug Name |
PYRIPYROPENE A
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [527340] | ||
| Formula |
C31H35NO10
|
||||
| Canonical SMILES |
CC(=O)OCC1(C(CCC2(C1C=C(C3(C2C(=C4C(=CC(OC4=O)C5=CN=CC=<br />C5)O3)O)C)OC(=O)C)C)OC(=O)C)C
|
||||
| InChI |
1S/C31H35NO10/c1-16(33)38-15-30(5)22-13-24(40-18(3)35)31(6)27(29(22,4)10-9-23(30)39-17(2)34)26(36)25-21(42-31)12-20(41-28(25)37)19-8-7-11-32-14-19/h7-8,11-14,20,22-23,27,36H,9-10,15H2,1-6H3
|
||||
| InChIKey |
APXYGOOSELMEEZ-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Liver carboxylesterase | Target Info | Inhibitor | [527138] | |
| mRNA of human acyl CoA cholesterol acyl-transferase-2 | Target Info | Inhibitor | [527340] | ||
| PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
| Pathway Interaction Database | E2F transcription factor network | ||||
| References | |||||
| Ref 527138 | Bioorg Med Chem Lett. 2004 Aug 16;14(16):4277-80.Acyl-CoA: cholesterol acyltransferase inhibitory activities of fatty acid amides isolated from Mylabris phalerate Pallas. | ||||
| Ref 527340 | Bioorg Med Chem Lett. 2005 Jan 17;15(2):385-8.Saucerneol B derivatives as human acyl-CoA: cholesterol acyltransferase inhibitors. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.