Drug Information

Drug General Information
Drug ID
D0A1RG
Former ID
DNC011849
Drug Name
RIP
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533492]
Formula
C5H10O5
Canonical SMILES
C1C(C(C(C(O1)O)O)O)O
InChI
1S/C5H10O5/c6-2-1-10-5(9)4(8)3(2)7/h2-9H,1H2/t2-,3-,4-,5-/m1/s1
InChIKey
SRBFZHDQGSBBOR-TXICZTDVSA-N
PubChem Compound ID
441481
Target and Pathway
Target(s) Angiotensin-converting enzyme Target Info Inhibitor [533492]
KEGG Pathway Renin-angiotensin system
Chagas disease (American trypanosomiasis)
Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 533492J Med Chem. 1985 Nov;28(11):1553-5.Difluorostatine- and difluorostatone-containing peptides as potent and specific renin inhibitors.
Ref 533492J Med Chem. 1985 Nov;28(11):1553-5.Difluorostatine- and difluorostatone-containing peptides as potent and specific renin inhibitors.

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