Drug Information

Drug General Information
Drug ID
D0A1IL
Former ID
DNCL002497
Drug Name
VAL-083
Drug Type
Small molecular drug
Indication Acute myeloid leukemia; Grade IV malignant glioma [ICD9: 205, 191; ICD10:C92.0, C71] Phase 1/2 [523698]
Company
Del Mar Pharmaceuticals
Formula
C6H10O4
Canonical SMILES
C1C(O1)C(C(C2CO2)O)O
InChI
1S/C6H10O4/c7-5(3-1-9-3)6(8)4-2-10-4/h3-8H,1-2H2/t3-,4+,5+,6-
InChIKey
AAFJXZWCNVJTMK-GUCUJZIJSA-N
PubChem Compound ID
15942827
PubChem Substance ID
22395820, 46480551, 54210077, 57379548, 126642673, 134994209, 163621017, 163686348, 184811954, 194175383, 230248686, 249582789
Target and Pathway
Target(s) Human DNA Target Info Modulator [533557]
References
Ref 523698ClinicalTrials.gov (NCT01478178) Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma. U.S. National Institutes of Health.
Ref 533557Effect of 1,2:5,6-dianhydrogalactitol and 1,2:5,6-dianhydro-3,4-diacetylgalactitol on DNA synthesis in the cells of melanoma B16, bone marrow, small intestine epithelium, spleen and liver of mice. Biull Eksp Biol Med. 1984 Sep;98(9):301-3.

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