Drug Information

Drug General Information
Drug ID
D09VSK
Former ID
DNC005672
Drug Name
4-(1H-Indol-3-ylmethyl)-phenylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527501]
Formula
C15H14N2
Canonical SMILES
C1=CC=C2C(=C1)C(=CN2)CC3=CC=C(C=C3)N
InChI
1S/C15H14N2/c16-13-7-5-11(6-8-13)9-12-10-17-15-4-2-1-3-14(12)15/h1-8,10,17H,9,16H2
InChIKey
KDXYOBVEKNURNB-UHFFFAOYSA-N
PubChem Compound ID
4301799
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [527501]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 527501Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91.Binding of isotryptamines and indenes at h5-HT6 serotonin receptors.
Ref 527501Bioorg Med Chem Lett. 2005 Apr 15;15(8):1987-91.Binding of isotryptamines and indenes at h5-HT6 serotonin receptors.

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