Drug Information

Drug General Information
Drug ID
D09TFN
Former ID
DIB020204
Drug Name
LDC1267
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532677]
Formula
C30H26F2N4O5
InChI
InChI=1S/C30H26F2N4O5/c1-5-40-28-16-36(23-8-6-18(31)12-17(23)2)35-29(28)30(37)34-19-7-9-25(21(32)13-19)41-24-10-11-33-22-15-27(39-4)26(38-3)14-20(22)24/h6-16H,5H2,1-4H3,(H,34,37)
InChIKey
ISPBCAXOSOLFME-UHFFFAOYSA-N
PubChem Compound ID
56847486
PubChem Substance ID
135379148, 226529852, 242078848, 249565927, 252451642
Target and Pathway
Target(s) Tyrosine-protein kinase receptor UFO Target Info Inhibitor [532677]
TYRO3 protein tyrosine kinase Target Info Inhibitor [532677]
Mertk Target Info Inhibitor [532677]
NetPath Pathway FSH Signaling PathwayNetPath_23:TSH Signaling Pathway
Pathway Interaction Database Validated transcriptional targets of deltaNp63 isoforms
Reactome VEGFA-VEGFR2 PathwayR-HSA-202733:Cell surface interactions at the vascular wall
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBaseWP1794:Cell surface interactions at the vascular wall
References
Ref 532677The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature. 2014 Mar 27;507(7493):508-12.
Ref 532677The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature. 2014 Mar 27;507(7493):508-12.

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