Drug Information

Drug General Information
Drug ID
D09JXH
Former ID
DIB008576
Drug Name
LUM001
Synonyms
SHP625
Indication Primary biliary cirrhosis [ICD9: 571.6; ICD10:K74.3] Phase 2 [525031]
Company
Lumena pharmaceuticals
Target and Pathway
Target(s) Ileal bile acid transfer Target Info Inhibitor [550354]
KEGG Pathway Bile secretion
Reactome Recycling of bile acids and salts
WikiPathways Bile acid and bile salt metabolism
References
Ref 525031ClinicalTrials.gov (NCT02321306) An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis. U.S. National Institutes of Health.
Ref 550354Current research on the treatment of primary sclerosing cholangitis. Intractable Rare Dis Res. 2015 Feb; 4(1): 1-6.

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