Drug Information

Drug General Information
Drug ID
D08WTR
Former ID
DIB018679
Drug Name
6-iodo-nordihydrocapsaicin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467454]
Formula
C17H26INO3
InChI
InChI=1S/C17H26INO3/c1-12(2)7-5-4-6-8-17(21)19-11-13-9-16(22-3)15(20)10-14(13)18/h9-10,12,20H,4-8,11H2,1-3H3,(H,19,21)
InChIKey
MGJQSBQUFTWMOG-UHFFFAOYSA-N
PubChem Compound ID
24881008
PubChem Substance ID
50136685, 57454678, 178100932
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Blocker (channel blocker) [543861]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 467454(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4110).
Ref 543861(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 507).

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