Drug Information

Drug General Information
Drug ID
D08WIJ
Former ID
DNC006240
Drug Name
8-methyl-2-morpholino-7-phenoxy-4H-chromen-4-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527870]
Formula
C20H19NO4
Canonical SMILES
CC1=C(C=CC2=C1OC(=CC2=O)N3CCOCC3)OC4=CC=CC=C4
InChI
1S/C20H19NO4/c1-14-18(24-15-5-3-2-4-6-15)8-7-16-17(22)13-19(25-20(14)16)21-9-11-23-12-10-21/h2-8,13H,9-12H2,1H3
InChIKey
OOXOMHKMWGSWSD-UHFFFAOYSA-N
PubChem Compound ID
23586753
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase A Target Info Inhibitor [527870]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 527870Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.
Ref 527870Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.

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