Drug Information

Drug General Information
Drug ID
D08VBE
Former ID
DIB020194
Drug Name
LB42908
Synonyms
LB 42908
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526198]
Formula
C32H33N5O3
InChI
InChI=1S/C32H33N5O3/c1-34-11-13-36(14-12-34)32(38)29-20-35(19-28(29)27-8-4-6-24-5-2-3-7-26(24)27)18-25-16-33-21-37(25)17-23-9-10-30-31(15-23)40-22-39-30/h2-10,15-16,19-21,30-31H,11-14,17-18,22H2,1H3
InChIKey
VZWZHIJGBPHRDI-UHFFFAOYSA-N
PubChem Compound ID
91623355
PubChem Substance ID
249565708
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [526198]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
References
Ref 526198A novel class of highly potent, selective, and non-peptidic inhibitor of Ras farnesyltransferase (FTase). Bioorg Med Chem Lett. 2001 Dec 3;11(23):3069-72.
Ref 526198A novel class of highly potent, selective, and non-peptidic inhibitor of Ras farnesyltransferase (FTase). Bioorg Med Chem Lett. 2001 Dec 3;11(23):3069-72.

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