Drug Information

Drug General Information
Drug ID
D08NRG
Former ID
DIB008656
Drug Name
HYP-10
Synonyms
T-type calcium channel blockers (pain), Ewha Woman's University
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Investigative [543872]
Company
Ewha Woman's University
Canonical SMILES
C(=O)(CCCN)N1CCN(CC1)C(c1ccccc1)c1ccc(cc1)Cl
Target and Pathway
Target(s) Voltage-dependent T-type calcium channel subunit alpha-1H Target Info Blocker [543872]
KEGG Pathway MAPK signaling pathway
Calcium signaling pathway
Circadian entrainment
PathWhiz Pathway Muscle/Heart Contraction
Reactome NCAM1 interactions
WikiPathways Corticotropin-releasing hormone
NCAM signaling for neurite out-growth
References
Ref 543872(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 536).
Ref 543872(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 536).

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