Drug Information

Drug General Information
Drug ID
D08MHU
Former ID
DNC011389
Drug Name
6-Hydroxy-2-(4-hydroxy-benzyl)-chromen-4-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525506]
Formula
C16H12O4
Canonical SMILES
C1=CC(=CC=C1CC2=CC(=O)C3=C(O2)C=CC(=C3)O)O
InChI
1S/C16H12O4/c17-11-3-1-10(2-4-11)7-13-9-15(19)14-8-12(18)5-6-16(14)20-13/h1-6,8-9,17-18H,7H2
InChIKey
LSIKXKVRDNWDKN-UHFFFAOYSA-N
PubChem Compound ID
10539813
Target and Pathway
Target(s) Aldose reductase Target Info Inhibitor [525506]
BioCyc Pathway Methylglyoxal degradation III
Acetone degradation I (to methylglyoxal)
KEGG Pathway Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Glycerolipid metabolism
Metabolic pathways
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Fructose and Mannose Degradation
Pyruvate Metabolism
Pterine Biosynthesis
Glycerolipid Metabolism
Galactose Metabolism
WikiPathways Metapathway biotransformation
Polyol Pathway
Metabolism of steroid hormones and vitamin D
References
Ref 525506J Med Chem. 1999 Jun 3;42(11):1881-93.1-Benzopyran-4-one antioxidants as aldose reductase inhibitors.
Ref 525506J Med Chem. 1999 Jun 3;42(11):1881-93.1-Benzopyran-4-one antioxidants as aldose reductase inhibitors.

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