Drug Information

Drug General Information
Drug ID
D08KDK
Former ID
DIB016796
Drug Name
T-2007
Synonyms
DPB sodium; Diphenylbarbituric sodium; Diphenylbarbituric acid (epilepsy), Taro; 5,5-diphenylbarbituric sodium
Indication Epilepsy [ICD10:G40] Phase 2 [522725]
Company
Taro Pharmaceutical Industries Ltd
Canonical SMILES
C1(C(=O)NC(=O)NC1=O)(c1ccccc1)c1ccccc1.[Na+]
Target and Pathway
Target(s) GABA A receptor Target Info Agonist [543814]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 522725ClinicalTrials.gov (NCT00939653) T2007-002 Clofarabine, Etoposide, Cyclophosphamide in Relapsed Acute Myelogenous Leukemia (AML). U.S. National Institutes of Health.
Ref 543814(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).

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