Drug Information

Drug General Information
Drug ID
D08DWH
Former ID
DIB007449
Drug Name
Idrapril
Synonyms
LG-32001
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Discontinued in Phase 2 [545074]
Company
Laboratorio Guidotti SpA
Formula
C11H18N2O5
Canonical SMILES
C(=O)([C@H]1[C@@H](C(=O)O)CCCC1)N(CC(=O)NO)C
CAS Number
CAS 127420-24-0
PubChem Compound ID
65960
Target and Pathway
Target(s) Angiotensin-converting enzyme Target Info Inhibitor [526807]
KEGG Pathway Renin-angiotensin system
Chagas disease (American trypanosomiasis)
Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 545074Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002045)
Ref 526807Pharmacology of idrapril: a new class of angiotensin converting enzyme inhibitors. J Cardiovasc Pharmacol. 1992 Jul;20(1):139-46.

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