Drug Information

Drug General Information
Drug ID
D08DFU
Former ID
DIB008165
Drug Name
CMX-157
Synonyms
Hexadecyloxypropyl tenofovir
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Phase 1 [522964]
Company
Chimerix
Formula
C28H52N5O5P
Canonical SMILES
P(=O)(O)(CO[C@@H](Cn1c2ncnc(c2nc1)N)C)OCCCOCCCCCCCCCCCC<br />CCCC
PubChem Compound ID
56841860
Target and Pathway
Target(s) HIV reverse transcriptase Target Info Inhibitor [544301]
References
Ref 522964ClinicalTrials.gov (NCT01080820) A Safety, Tolerability and Pharmacokinetic Study of a Single Dose of CMX157 in Healthy Volunteers. U.S. National Institutes of Health.
Ref 544301Practical Considerations For Developing Nucleoside Reverse Transcriptase Inhibitors. Drug Discov Today Technol. 2012 Autumn; 9(3): e183-e193.

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