Drug Information

Drug General Information
Drug ID
D08AGA
Former ID
DNC011822
Drug Name
3-((S)-Azetidin-2-yloxy)-5-iodo-pyridine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527014]
Formula
C8H9IN2O
Canonical SMILES
C1CNC1OC2=CC(=CN=C2)I
InChI
1S/C8H9IN2O/c9-6-3-7(5-10-4-6)12-8-1-2-11-8/h3-5,8,11H,1-2H2/t8-/m0/s1
InChIKey
KSOZTGQWGPTPSV-QMMMGPOBSA-N
PubChem Compound ID
44297909
Target and Pathway
Target(s) Neuronal acetylcholinereceptor subunit alpha-2 Target Info Inhibitor [527014]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Nicotinic acetylcholine receptor signaling pathway
Reactome Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 527014Bioorg Med Chem Lett. 2004 Apr 19;14(8):1845-8.Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.
Ref 527014Bioorg Med Chem Lett. 2004 Apr 19;14(8):1845-8.Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.

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