Drug Information

Drug General Information
Drug ID
D07ZNR
Former ID
DNC011674
Drug Name
2,3,5,6-Tetrafluoro-4-pentafluorophenylazo-phenol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532449]
Formula
C12HF9N2O
Canonical SMILES
C1(=C(C(=C(C(=C1F)F)F)F)F)NN=C2C(=C(C(=O)C(=C2F)F)F)F
InChI
1S/C12HF9N2O/c13-1-2(14)4(16)10(5(17)3(1)15)22-23-11-6(18)8(20)12(24)9(21)7(11)19/h22H
InChIKey
FNPGFLBPXIANTH-UHFFFAOYSA-N
PubChem Compound ID
5490028
Target and Pathway
Target(s) 17 alpha-hydroxylase-C17, 20-lyase Target Info Inhibitor [532449]
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Target Info Inhibitor [532449]
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Target Info Inhibitor [532449]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Glucocorticoid biosynthesis
Androgen biosynthesisPWY-7305:Superpathway of steroid hormone biosynthesis
Allopregnanolone biosynthesis
Androgen biosynthesis
KEGG Pathway Steroid hormone biosynthesis
Metabolic pathways
Ovarian steroidogenesis
Prolactin signaling pathwayhsa00140:Steroid hormone biosynthesis
Prostate cancerhsa00140:Steroid hormone biosynthesis
NetPath Pathway IL2 Signaling Pathway
PathWhiz Pathway Androgen and Estrogen Metabolism
SteroidogenesisPW000045:Androgen and Estrogen Metabolism
Reactome Androgen biosynthesis
Glucocorticoid biosynthesis
Endogenous sterolsR-HSA-193048:Androgen biosynthesisR-HSA-193048:Androgen biosynthesis
WikiPathways Metapathway biotransformation
Steroid Biosynthesis
Oxidation by Cytochrome P450
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
Prostate Cancer
Phase 1 - Functionalization of compounds
References
Ref 532449J Med Chem. 1990 Sep;33(9):2452-5.Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis.
Ref 532449J Med Chem. 1990 Sep;33(9):2452-5.Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis.

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