Drug Information

Drug General Information
Drug ID
D07PYV
Former ID
DNC008849
Drug Name
2-aminopyridine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530216]
Formula
C5H6N2
Canonical SMILES
C1=CC=NC(=C1)N
InChI
1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)
InChIKey
ICSNLGPSRYBMBD-UHFFFAOYSA-N
PubChem Compound ID
10439
Target and Pathway
Target(s) Nitric-oxide synthase, brain Target Info Inhibitor [530216]
BioCyc Pathway Citrulline-nitric oxide cycle
KEGG Pathway Arginine and proline metabolism
Metabolic pathways
Calcium signaling pathway
Phagosome
Circadian entrainment
Long-term depression
Salivary secretion
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
NetPath Pathway EGFR1 Signaling Pathway
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Arginine and Proline Metabolism
Reactome ROS production in response to bacteria
Nitric oxide stimulates guanylate cyclase
WikiPathways Monoamine Transport
Myometrial Relaxation and Contraction Pathways
Amyotrophic lateral sclerosis (ALS)
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
Spinal Cord Injury
Alzheimers Disease
Effects of Nitric Oxide
Serotonin Transporter Activity
References
Ref 530216J Med Chem. 2009 Jul 23;52(14):4533-7.L337H mutant of rat neuronal nitric oxide synthase resembles human neuronal nitric oxide synthase toward inhibitors.
Ref 530216J Med Chem. 2009 Jul 23;52(14):4533-7.L337H mutant of rat neuronal nitric oxide synthase resembles human neuronal nitric oxide synthase toward inhibitors.

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