Drug Information

Drug General Information
Drug ID
D07GWS
Former ID
DNC000173
Drug Name
Alanosine
Drug Type
Small molecular drug
Indication Discovery agent Phase 2 [521559]
Formula
C3H7N3O4
Canonical SMILES
C(C(C(=O)O)N)N(N=O)O
InChI
1S/C3H7N3O4/c4-2(3(7)8)1-6(10)5-9/h2,10H,1,4H2,(H,7,8)
InChIKey
MLFKVJCWGUZWNV-UHFFFAOYSA-N
CAS Number
CAS 475-38-7
PubChem Compound ID
98513
PubChem Substance ID
482981, 559469, 7506783, 8137413, 8140284, 10229805, 11405478, 11408691, 12015173, 44428777, 50025452, 50325474, 57336713, 103124646, 103193246, 104423122, 117543580, 125566931, 125809880, 128611925, 134339683, 135056893, 137088039, 139036460, 162253745, 162546986, 164835164, 179225486, 231597823
Target and Pathway
Target(s) Adenylosuccinate synthetase Target Info Inhibitor [536240]
References
Ref 521559ClinicalTrials.gov (NCT00062283) Alanosine in Treating Patients With Cancer. U.S. National Institutes of Health.
Ref 536240Lack of methylthioadenosine phosphorylase expression in mantle cell lymphoma is associated with shorter survival: implications for a potential targeted therapy. Clin Cancer Res. 2006 Jun 15;12(12):3754-61.

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