Drug Information

Drug General Information
Drug ID
D06UPT
Former ID
DNC002616
Drug Name
Sri-9439
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551391]
Formula
C18H17N7
Canonical SMILES
CC1=C2C(=NC(=NC2=NC=C1CNC3=CC=CC4=C3C=CC=N4)N)N
InChI
1S/C18H17N7/c1-10-11(9-23-17-15(10)16(19)24-18(20)25-17)8-22-14-6-2-5-13-12(14)4-3-7-21-13/h2-7,9,22H,8H2,1H3,(H4,19,20,23,24,25)
InChIKey
KMSATRJZEXNGDP-UHFFFAOYSA-N
PubChem Compound ID
446752
PubChem Substance ID
616333, 824483, 6597957, 7888649, 17183201, 36889095, 46506145, 50917439, 57404763, 103396454, 104003223, 104636982, 137184816, 160966485, 247335490
Target and Pathway
Target(s) Dihydrofolate reductase Target Info Inhibitor [551391]
PathWhiz Pathway Folate Metabolism
Pterine Biosynthesis
Reactome E2F mediated regulation of DNA replication
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Metabolism of folate and pterines
G1/S-Specific Transcription
References
Ref 551391DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-4. Nucleic Acids Res. 2011 January
Ref 551391DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-4. Nucleic Acids Res. 2011 January

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.