Drug Information

Drug General Information
Drug ID
D06RBN
Former ID
DIB011144
Drug Name
Protein vaccines
Synonyms
Vaccines; Protein vaccines (cancer)
Drug Type
Vaccine
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 1 [551003]
Company
ImmunoFrontier Inc
Target and Pathway
Target(s) T-cell surface glycoprotein CD8 Target Info [526971]
T-cell surface glycoprotein CD4 Target Info [526971]
KEGG Pathway Cell adhesion molecules (CAMs)
Antigen processing and presentation
Hematopoietic cell lineage
T cell receptor signaling pathway
Primary immunodeficiencyhsa04514:Cell adhesion molecules (CAMs)
Primary immunodeficiency
NetPath Pathway Leptin Signaling Pathway
Pathway Interaction Database TCR signaling in na&#xef
IL12-mediated signaling events
CXCR4-mediated signaling events
C-MYB transcription factor network
IL23-mediated signaling events
Arf1 pathway
Notch-mediated HES/HEY network
IL12 signaling mediated by STAT4
Reactome Binding and entry of HIV virion
Phosphorylation of CD3 and TCR zeta chains
Translocation of ZAP-70 to Immunological synapse
Generation of second messenger molecules
PD-1 signaling
WikiPathways TCR Signaling Pathway
Cytokines and Inflammatory Response
Host Interactions of HIV factors
Defensins
HIV Life Cycle
TCR signaling
Costimulation by the CD28 family
References
Ref 551003Clinical pipeline report, company report or official report of ImmunoFrontier Inc.
Ref 526971Vaccine-induced CD4+ T cell responses to MAGE-3 protein in lung cancer patients. J Immunol. 2004 Mar 1;172(5):3289-96.

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