Drug Information

Drug General Information
Drug ID
D06RBJ
Former ID
DIB013073
Drug Name
DIPROTEVERINE HYDROCHLORIDE
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Phase 3 [530977]
Formula
C26H36ClNO4
Canonical SMILES
CCOC1=C(C=C(C=C1)CC2=NCCC3=CC(=C(C=C32)OC(C)C)OC(C)C)OC<br />C.Cl
InChI
1S/C26H35NO4.ClH/c1-7-28-23-10-9-19(14-24(23)29-8-2)13-22-21-16-26(31-18(5)6)25(30-17(3)4)15-20(21)11-12-27-22;/h9-10,14-18H,7-8,11-13H2,1-6H3;1H
InChIKey
AWQPJKUSDUHYIX-UHFFFAOYSA-N
CAS Number
CAS 69373-88-2
PubChem Compound ID
3052867
PubChem Substance ID
10056165, 15257139, 36118775, 49986529, 57353989, 74592962, 111619284, 135131117, 198965986, 232943253
Target and Pathway
Target(s) Calcium channel Target Info Antagonist [534306], [551871]
References
Ref 530977Diproteverine (BRL 40015): a new type of calcium antagonist with potential antianginal properties. Eur J Pharmacol. 1991 Jan 17;192(3):317-27.
Ref 534306Prenatal toxicity studies in rats and rabbits with the calcium channel blocker diproteverine. Reprod Toxicol. 1996 Jan-Feb;10(1):43-9.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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