Drug Information

Drug General Information
Drug ID
D06HKB
Former ID
DIB011572
Drug Name
Lodenosine
Synonyms
FddA; FddI; F-ddN; Fdd analogs, NIH/US Bioscience
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Discontinued in Phase 2 [545946]
Company
National Cancer Institute
Formula
C10H12FN5O2
Canonical SMILES
n1(c2c(nc1)c(ncn2)N)[C@@H]1O[C@@H](C[C@@H]1F)CO
CAS Number
CAS 110143-10-7
PubChem Compound ID
72180
Target and Pathway
Target(s) HIV reverse transcriptase Target Info Inhibitor [532937]
References
Ref 545946Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005453)
Ref 5329372?,3?-Dialdehyde of ATP, ADP, and adenosine inhibit HIV-1 reverse transcriptase and HIV-1 replication. Curr HIV Res. 2014;12(5):347-58.

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