Drug Information

Drug General Information
Drug ID
D06AFP
Former ID
DNC004978
Drug Name
N-Hydroxy-2-(naphthalen-2-ylsulfanyl)-acetamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527322]
Formula
C12H11NO2S
Canonical SMILES
C1=CC=C2C=C(C=CC2=C1)SCC(=O)NO
InChI
1S/C12H11NO2S/c14-12(13-15)8-16-11-6-5-9-3-1-2-4-10(9)7-11/h1-7,15H,8H2,(H,13,14)
InChIKey
GNDJOJQVOFQQBM-UHFFFAOYSA-N
PubChem Compound ID
11436221
Target and Pathway
Target(s) Aminopeptidase N Target Info Inhibitor [527322]
BioCyc Pathway Glutathione-mediated detoxification
KEGG Pathway Glutathione metabolism
Metabolic pathways
Renin-angiotensin system
Hematopoietic cell lineage
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Glutathione Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways Metabolism of Angiotensinogen to Angiotensins
Cardiac Progenitor Differentiation
miR-targeted genes in squamous cell - TarBase
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
Glutathione metabolism
References
Ref 527322Bioorg Med Chem Lett. 2005 Jan 3;15(1):181-3.N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity.
Ref 527322Bioorg Med Chem Lett. 2005 Jan 3;15(1):181-3.N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity.

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