Drug Information

Drug General Information
Drug ID
D05XLD
Former ID
DNC008431
Drug Name
Piridronic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540162]
Formula
C7H11NO6P2
InChI
InChI=1S/C7H11NO6P2/c9-15(10,11)7(16(12,13)14)5-6-3-1-2-4-8-6/h1-4,7H,5H2,(H2,9,10,11)(H2,12,13,14)
InChIKey
NGMZSXZBZNXBGX-UHFFFAOYSA-N
PubChem Compound ID
57637
PubChem Substance ID
8185350, 15197241, 43115307, 76483666, 103313949, 104313190, 117401064, 126421310, 128699093, 134345636, 135026996, 135650705, 142216117, 160852197, 179323430, 198949788, 226576473
Target and Pathway
Target(s) Farnesyl pyrophosphatesynthetase Target Info Inhibitor [529362]
KEGG Pathway Terpenoid backbone biosynthesis
Metabolic pathways
Biosynthesis of antibiotics
Influenza A
HTLV-I infection
PathWhiz Pathway Steroid Biosynthesis
Reactome Cholesterol biosynthesis
Activation of gene expression by SREBF (SREBP)
WikiPathways Activation of Gene Expression by SREBP (SREBF)
SREBP signalling
Cholesterol Biosynthesis
References
Ref 540162(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3183).
Ref 529362J Med Chem. 2008 Apr 10;51(7):2187-95. Epub 2008 Mar 8.Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.