Drug Information

Drug General Information
Drug ID
D05VSK
Former ID
DNC010061
Drug Name
ETHOXYCOUMARIN
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530514]
Formula
C11H10O3
Canonical SMILES
CCOC1=CC2=C(C=C1)C=CC(=O)O2
InChI
1S/C11H10O3/c1-2-13-9-5-3-8-4-6-11(12)14-10(8)7-9/h3-7H,2H2,1H3
InChIKey
LIFAQMGORKPVDH-UHFFFAOYSA-N
PubChem Compound ID
35703
Target and Pathway
Target(s) Carbonic anhydrase Target Info Inhibitor [530514]
Carbonic anhydrase IX Target Info Inhibitor [530514]
Carbonic anhydrase XIV Target Info Inhibitor [530514]
Carbonic anhydrase XII Target Info Inhibitor [530514]
KEGG Pathway Nitrogen metabolismhsa00910:Nitrogen metabolismhsa00910:Nitrogen metabolism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database HIF-1-alpha transcription factor network
Reactome Regulation of gene expression by Hypoxia-inducible Factor
Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxideR-HSA-1475029:Reversible hydration of carbon dioxide
WikiPathways Vitamin D Receptor Pathway
Reversible Hydration of Carbon Dioxide
Regulation of Hypoxia-inducible Factor (HIF) by OxygenWP2770:Reversible Hydration of Carbon DioxideWP2770:Reversible Hydration of Carbon Dioxide
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 530514J Med Chem. 2010 Jan 14;53(1):335-44.Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.
Ref 530514J Med Chem. 2010 Jan 14;53(1):335-44.Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.