Drug Information

Drug General Information
Drug ID
D05TIS
Former ID
DNC003447
Drug Name
Glucose-6-Phosphate
Drug Type
Small molecular drug
Indication Discovery agent Phase 1 [467886], [523177]
Formula
C6H13O9P
InChI
InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6?/m1/s1
InChIKey
NBSCHQHZLSJFNQ-GASJEMHNSA-N
CAS Number
CAS 56-73-5
PubChem Compound ID
5958
PubChem Substance ID
3392, 841544, 8153701, 16886971, 29214830, 29224981, 40649284, 49972744, 50257635, 92298604, 103806671, 104310725, 117392202, 126524026, 128679240, 135250158, 137008671, 162221893, 178101364, 225118020, 226432288, 252292774
Target and Pathway
Target(s) Glucosamine-6-phosphate synthase Target Info Inhibitor [551393]
References
Ref 467886(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4647).
Ref 523177ClinicalTrials.gov (NCT01205178) G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine). U.S. National Institutes of Health.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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