Drug Information

Drug General Information
Drug ID
D05OIF
Former ID
DIB020519
Drug Name
N-ethylhistamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538786]
Formula
C7H13N3
InChI
InChI=1S/C7H13N3/c1-2-10-5-7(3-4-8)9-6-10/h5-6H,2-4,8H2,1H3
InChIKey
LIXGKSRWGHVUHT-UHFFFAOYSA-N
PubChem Compound ID
44292270
PubChem Substance ID
89998131, 103228465, 132620443, 135650396, 137142568, 137481058, 162858806, 224074881, 226893489, 247396097, 247824128
Target and Pathway
Target(s) Histamine H4 receptor Target Info Agonist [527985]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538786(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1271).
Ref 527985Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives. Br J Pharmacol. 2006 Apr;147(7):744-54.

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