Drug Information

Drug General Information
Drug ID
D05NOG
Former ID
DIB008667
Drug Name
Targeted ranpirnase conjugates
Synonyms
AC RN-321; RN-321; RRNP-EGF; Targeted ranpirnase conjugates (cancer); Polyanhydride-bound Onconase, Alfacell; Polyanhydride-bound ranpirnase, Alfacell; Targeted Onconase conjugates (cancer), Alfacell; Targeted ranpirnase conjugates (cancer), Alfacell; Onconase-mAb conjugate, Alfacell/NCI; Ranpirnase-mAb conjugate, Alfacell/NCI
Drug Type
Antibody
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Preclinical [548045]
Company
Tamir Biotechnology Inc
Target and Pathway
Target(s) B-cell receptor CD22 Target Info [550223]
KEGG Pathway Cell adhesion molecules (CAMs)
Hematopoietic cell lineage
B cell receptor signaling pathway
PANTHER Pathway B cell activation
Pathway Interaction Database BCR signaling pathway
Reactome Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
WikiPathways B Cell Receptor Signaling Pathway
References
Ref 548045Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021480)
Ref 550223Clinical pipeline report, company report or official report of Alfacell.

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