Drug Information

Drug General Information
Drug ID
D05COG
Former ID
DIB013764
Drug Name
DU-1777
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Terminated [545072]
Company
Dainippon Pharmaceutical Co Ltd
Formula
C26H37N5O7
Canonical SMILES
N1([C@@H](C[C@H]2[C@@H]1CCCC2)C(=O)O)C(=O)CC[C@@H](NC(=<br />O)[C@@H](NC(=O)c1cnccc1)CCCCN)C(=O)O
CAS Number
CAS 116662-73-8
PubChem Compound ID
3081108
Target and Pathway
Target(s) Angiotensin-converting enzyme Target Info Inhibitor [533641]
KEGG Pathway Renin-angiotensin system
Chagas disease (American trypanosomiasis)
Hypertrophic cardiomyopathy (HCM)
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 545072Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002041)
Ref 533641Antihypertensive properties of a new long-acting angiotensin converting enzyme inhibitor in renin-dependent and independent hypertensive models. Arzneimittelforschung. 1995 Aug;45(8):853-8.

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