Drug Information

Drug General Information
Drug ID
D05BPC
Former ID
DIB006927
Drug Name
Tiprelestat
Synonyms
Elafin; Recombinant leukocyte elastase/proteinase-3 inhibitor (iv, inflammation), Proteo Biotech
Indication Myocardial infarction [ICD9: 410; ICD10:I21, I22] Phase 2 [548073]
Company
Proteo Biotech AG
Formula
C254H416N72O75S10
PubChem Compound ID
44201346
Target and Pathway
Target(s) Leukocyte proteinase-3 Target Info Modulator
Leukocyte elastase Target Info Modulator
KEGG Pathway Transcriptional misregulation in cancer
Systemic lupus erythematosus
Pathway Interaction Database C-MYB transcription factor networkupa_upar_pathway:Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
C-MYB transcription factor network
Reactome Common Pathway of Fibrin Clot FormationR-HSA-1442490:Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
WikiPathways Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Human Complement System
Degradation of collagen
References
Ref 548073Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021706)

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