Drug Information

Drug General Information
Drug ID
D05BBQ
Former ID
DIB005492
Drug Name
RP-66364
Synonyms
RP-60532; RP-69929
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Terminated [545586]
Company
Rhone-Poulenc SA
Canonical SMILES
c1(c(oc(n1)CCCCCCc1nn[nH]n1)c1ccc(cc1)OC)c1ccc(cc1)OC
CAS Number
CAS 186912-92-5
Target and Pathway
Target(s) Leukotriene B4 receptor 1 Target Info Modulator [550934]
Cyclooxygenase Target Info Modulator [550934]
KEGG Pathway Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
Reactome Leukotriene receptors
G alpha (q) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
GPCR ligand binding
GPCR downstream signaling
References
Ref 545586Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003795)
Ref 550934WO patent application no. 1997,0297,75, Compositions comprising a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist.

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