Drug Information

Drug General Information
Drug ID
D04YIV
Former ID
DNC014528
Drug Name
2-(Phenylsulfonamido)acetic Acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531207]
Formula
C8H9NO4S
Canonical SMILES
C1=CC=C(C=C1)S(=O)(=O)NCC(=O)O
InChI
1S/C8H9NO4S/c10-8(11)6-9-14(12,13)7-4-2-1-3-5-7/h1-5,9H,6H2,(H,10,11)
InChIKey
WTSZSAHZIMPSDM-UHFFFAOYSA-N
PubChem Compound ID
220662
Target and Pathway
Target(s) Aldose reductase Target Info Inhibitor [531207]
BioCyc Pathway Methylglyoxal degradation III
Acetone degradation I (to methylglyoxal)
KEGG Pathway Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Glycerolipid metabolism
Metabolic pathways
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Fructose and Mannose Degradation
Pyruvate Metabolism
Pterine Biosynthesis
Glycerolipid Metabolism
Galactose Metabolism
WikiPathways Metapathway biotransformation
Polyol Pathway
Metabolism of steroid hormones and vitamin D
References
Ref 531207J Med Chem. 2010 Nov 11;53(21):7756-66.A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
Ref 531207J Med Chem. 2010 Nov 11;53(21):7756-66.A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.

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