Drug Information

Drug General Information
Drug ID
D04UOP
Former ID
DNC000359
Drug Name
Butoxamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535096]
Formula
C15H25NO3
Canonical SMILES
CC(C(C1=C(C=CC(=C1)OC)OC)O)NC(C)(C)C
InChI
1S/C15H25NO3/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6/h7-10,14,16-17H,1-6H3/t10-,14+/m1/s1
InChIKey
TWUSDDMONZULSC-YGRLFVJLSA-N
CAS Number
CAS 7518-13-0
PubChem Compound ID
688388
PubChem Substance ID
44872257, 78105473, 109891546
Target and Pathway
Target(s) Beta-2 adrenergic receptor Target Info Antagonist [535096]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta2 adrenergic receptor signaling pathway
Pathway Interaction Database Arf6 trafficking events
Arf6 signaling events
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Vitamin D Receptor Pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 535096Partial agonistic effects of carteolol on atypical beta-adrenoceptors in the guinea pig gastric fundus. Jpn J Pharmacol. 2000 Nov;84(3):287-92.
Ref 535096Partial agonistic effects of carteolol on atypical beta-adrenoceptors in the guinea pig gastric fundus. Jpn J Pharmacol. 2000 Nov;84(3):287-92.

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