Drug Information

Drug General Information
Drug ID
D04UCV
Former ID
DNC004320
Drug Name
8-Chloro-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526235]
Formula
C11H11ClN2
Canonical SMILES
C1CN2C(=CC3=C2C=CC(=C3)Cl)CN1
InChI
1S/C11H11ClN2/c12-9-1-2-11-8(5-9)6-10-7-13-3-4-14(10)11/h1-2,5-6,13H,3-4,7H2
InChIKey
QKGDOWUCRMVFPY-UHFFFAOYSA-N
PubChem Compound ID
14595512
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Inhibitor [526235]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 526235Bioorg Med Chem Lett. 2002 Jan 21;12(2):155-8.Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors.
Ref 526235Bioorg Med Chem Lett. 2002 Jan 21;12(2):155-8.Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors.

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