Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04FTL
|
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| Former ID |
DNC003253
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| Drug Name |
3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [551374] | ||
| Formula |
C14H10N4
|
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=C3N=C4C=CC=CC4=N3)NN2
|
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| InChI |
1S/C14H10N4/c1-2-6-10-9(5-1)13(18-17-10)14-15-11-7-3-4-8-12(11)16-14/h1-8,17-18H
|
||||
| InChIKey |
ULAJWYXWWHKJNG-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Serine/threonine-protein kinase Chk1 | Target Info | Inhibitor | [551374] | |
| Pathway Interaction Database | Fanconi anemia pathway | ||||
| p73 transcription factor network | |||||
| ATR signaling pathway | |||||
| Circadian rhythm pathway | |||||
| p53 pathway | |||||
| Reactome | Activation of ATR in response to replication stress | ||||
| Processing of DNA double-strand break ends | |||||
| Presynaptic phase of homologous DNA pairing and strand exchange | |||||
| G2/M DNA damage checkpoint | |||||
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | |||||
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | |||||
| References | |||||
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