Drug Information

Drug General Information
Drug ID
D04EDO
Former ID
DIB020047
Drug Name
improgan
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538789]
Formula
C9H14N6
InChI
InChI=1S/C9H14N6/c1-11-9(14-6-10)13-4-2-3-8-5-12-7-15-8/h5,7H,2-4H2,1H3,(H,12,15)(H2,11,13,14)
InChIKey
CXTGREPICTYOGB-UHFFFAOYSA-N
PubChem Compound ID
10058807
PubChem Substance ID
15042863, 44175843, 79430011, 127693196, 135650387, 135653387, 194183886
Target and Pathway
Target(s) Histamine H4 receptor Target Info Agonist [525965]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538789(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1276).
Ref 525965Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol Pharmacol. 2001 Mar;59(3):434-41.

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