Drug Information

Drug General Information
Drug ID
D04AUA
Former ID
DIB001385
Drug Name
MIV-170
Synonyms
MIV-140; MSK-076; Non-nucleoside reverse transcriptase inhibitors, Medivir; HIV polymerase inhibitors, Medivir/Bristol-Myers Squibb; NNRTIs (HIV infection), Medivir/Bristol-Myers Squibb
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Terminated [547796]
Company
Medivir AB
Formula
C24H21F2N3O4S
Canonical SMILES
O=S(=O)(c1ccc(Oc2cnc(NC(=O)N[C@@H]3[C@@H]4COc5c(ccc(c5[<br />C@H]34)F)F)cc2)cc1)N
PubChem Compound ID
71589251
Target and Pathway
Target(s) HIV reverse transcriptase Target Info Inhibitor [531011]
References
Ref 547796Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019379)
Ref 531011Inhibition of HIV-1 by non-nucleoside reverse transcriptase inhibitors via an induced fit mechanism-Importance of slow dissociation and relaxation rates for antiviral efficacy. Biochem Pharmacol. 2010 Oct 15;80(8):1133-40.

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